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Lp(a) in the news in the New York Times

HyperTension - Thu, 01/11/2018 - 22:26
NY Times (Anahad O'Connor): “Only a small percentage of physicians know about this,” she said. “The biggest challenge for patients is finding knowledgeable physicians who know about this and can help them.”
Categories: HyperTension.

Inhibitors of NMMT reduce obesity by increasing fat cell metabolism.

HyperTension - Tue, 01/09/2018 - 13:55
Biochem Pharmacol (Neelakantan et al): Research scientists at the University of Texas Medical Branch (UTMB) at Galveston say they developed a promising new drug that curbs obesity without dieting and, based upon preliminary study findings, they may be on their way to unleashing a breakthrough for the millions who struggle with their weight. "Treatment of diet-induced obese mice systemically with a potent NNMT inhibitor significantly reduced body weight and white adipose mass, decreased adipocyte size, and lowered plasma total cholesterol levels. Notably, administration of NNMT inhibitors did not impact total food intake nor produce any observable adverse effects."
Categories: HyperTension.

J-curve in BP studies is an artifact - similar to dose targeting bias in HEMO.

HyperTension - Thu, 01/04/2018 - 16:09
Circulation (Kalkman et al): Conclusions: Low on-treatment SBP levels are associated with increased cardiovascular events and all-cause mortality. This association is independent of the attained blood pressure level because the J curve aligns with the SBP target. Our results suggest that the benefit or risk associated with intensive blood pressure–lowering treatment can be established only via randomized clinical trials.
Categories: HyperTension.

Toxic algae now a nationwide threat.

HyperTension - Thu, 11/16/2017 - 19:22
AP: MONROE, Mich. (AP) — Competing in a bass fishing tournament two years ago, Todd Steele cast his rod from his 21-foot motorboat — unaware that he was being poisoned. A thick, green scum coated western Lake Erie. And Steele, a semipro angler, was sickened by it.
Categories: HyperTension.

HDCN server move still in progress

HyperTension - Mon, 11/13/2017 - 16:16
We are still in the process of moving our sever. The CME and CEU certificates don't yet work, so please hold off in taking any tests on the site. The old audio files from ASN and other meetings should work now. Suggest you use VLC player to access them -- even the old Windows Media player files as well as the Real Media files open well using this player. Get the VLC player at https://www.videolan.org/vlc/.
Categories: HyperTension.

HDCN moving its registration and CME server

HyperTension - Tue, 11/07/2017 - 20:43
We are in the process of moving our registration and CME server, www.hdcn.net and all emails related to this server. There may be problems for the next few days until this server move is finished.
Categories: HyperTension.